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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-9
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pubmed:abstractText |
Activated protein C (APC) is increasingly understood to have diverse regulatory functions in inflammation. However, the exact mechanism of action remains unclear in severe acute pancreatitis (SAP). The aim of this study was to demonstrate the effects of APC on expressions of thrombomodulin (TM) and endothelial cell protein C receptor (EPCR), and its subsequent effect on the severity of SAP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amylases,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Coagulation Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Protein C,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Taurocholic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Thrombomodulin,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/activated protein C receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1573-2568
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1599-609
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pubmed:meshHeading |
pubmed-meshheading:19680809-Acute Disease,
pubmed-meshheading:19680809-Amylases,
pubmed-meshheading:19680809-Animals,
pubmed-meshheading:19680809-Blood Coagulation Factors,
pubmed-meshheading:19680809-Disease Models, Animal,
pubmed-meshheading:19680809-Endothelial Cells,
pubmed-meshheading:19680809-Humans,
pubmed-meshheading:19680809-Immunohistochemistry,
pubmed-meshheading:19680809-Injections, Intravenous,
pubmed-meshheading:19680809-Interleukin-8,
pubmed-meshheading:19680809-Male,
pubmed-meshheading:19680809-Matrix Metalloproteinase 9,
pubmed-meshheading:19680809-Pancreas,
pubmed-meshheading:19680809-Pancreatitis,
pubmed-meshheading:19680809-Protein C,
pubmed-meshheading:19680809-RNA, Messenger,
pubmed-meshheading:19680809-Rats,
pubmed-meshheading:19680809-Rats, Sprague-Dawley,
pubmed-meshheading:19680809-Receptors, Cell Surface,
pubmed-meshheading:19680809-Severity of Illness Index,
pubmed-meshheading:19680809-Taurocholic Acid,
pubmed-meshheading:19680809-Thrombomodulin,
pubmed-meshheading:19680809-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19680809-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Activated protein C improves the severity of severe acute pancreatitis via up-regulating the expressions of endothelial cell protein C receptor and thrombomodulin.
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pubmed:affiliation |
Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
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pubmed:publicationType |
Journal Article
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