Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
2009-8-26
pubmed:abstractText
In this study, we synthesized some natural and semi-synthetic prenyloxyphenylpropanoids (e.g., acetophenones, benzoic and cinnamic acids, chalcones, and coumarins), and we assessed their in vivo neuroprotective activity, using the mouse maximal electroshock-induced seizure model (MES test). 7-Isopentenyloxycoumarin and (2E)-3-{4-[(3-methylbut-2-enyl)oxy]phenyl}prop-2-enoic acid, administered ip at a dose of 300 mg/kg, suppressed MES-induced seizures in mice in a time- and dose-dependent manner.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1464-3405
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5419-22
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents.
pubmed:affiliation
Dipartimento di Scienze del Farmaco, Università G. D'Annunzio di Chieti-Pescara, Via dei Vestini 31, 66013 Chieti Scalo (CH), Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't