Source:http://linkedlifedata.com/resource/pubmed/id/19679472
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
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pubmed:dateCreated |
2009-8-26
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pubmed:abstractText |
In this study, we synthesized some natural and semi-synthetic prenyloxyphenylpropanoids (e.g., acetophenones, benzoic and cinnamic acids, chalcones, and coumarins), and we assessed their in vivo neuroprotective activity, using the mouse maximal electroshock-induced seizure model (MES test). 7-Isopentenyloxycoumarin and (2E)-3-{4-[(3-methylbut-2-enyl)oxy]phenyl}prop-2-enoic acid, administered ip at a dose of 300 mg/kg, suppressed MES-induced seizures in mice in a time- and dose-dependent manner.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1464-3405
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5419-22
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pubmed:meshHeading |
pubmed-meshheading:19679472-Animals,
pubmed-meshheading:19679472-Anticonvulsants,
pubmed-meshheading:19679472-Dose-Response Relationship, Drug,
pubmed-meshheading:19679472-Electroshock,
pubmed-meshheading:19679472-Hemiterpenes,
pubmed-meshheading:19679472-Mice,
pubmed-meshheading:19679472-Phenyl Ethers,
pubmed-meshheading:19679472-Seizures
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pubmed:year |
2009
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pubmed:articleTitle |
Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents.
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pubmed:affiliation |
Dipartimento di Scienze del Farmaco, Università G. D'Annunzio di Chieti-Pescara, Via dei Vestini 31, 66013 Chieti Scalo (CH), Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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