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pubmed-article:19679424pubmed:abstractTextAs in arteries, venous endothelium modulates vessel homeostasis and tone. The effect of an arterialized environment on venous endothelial function remains poorly understood. In particular, regulation of saphenous vein graft (SVG) blood flow and lumen caliber remains undefined. We hypothesized that mature SVGs would exhibit endothelium-dependent, flow-mediated vasodilation (FMD). We further hypothesized that endothelium-derived nitric oxide (NO) was an important mediator.lld:pubmed
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pubmed-article:19679424pubmed:articleTitleIn vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.lld:pubmed
pubmed-article:19679424pubmed:affiliationDivision of Vascular and Endovascular Surgery, University of California San Francisco, San Francisco, CA 94143-0222, USA. Christopher.Owens@ucsfmedctr.orglld:pubmed
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