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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-11-2
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pubmed:abstractText |
As in arteries, venous endothelium modulates vessel homeostasis and tone. The effect of an arterialized environment on venous endothelial function remains poorly understood. In particular, regulation of saphenous vein graft (SVG) blood flow and lumen caliber remains undefined. We hypothesized that mature SVGs would exhibit endothelium-dependent, flow-mediated vasodilation (FMD). We further hypothesized that endothelium-derived nitric oxide (NO) was an important mediator.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1097-6809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1063-70
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pubmed:dateRevised |
2011-5-4
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pubmed:meshHeading |
pubmed-meshheading:19679424-Administration, Oral,
pubmed-meshheading:19679424-Brachial Artery,
pubmed-meshheading:19679424-Cohort Studies,
pubmed-meshheading:19679424-Endothelium, Vascular,
pubmed-meshheading:19679424-Enzyme Inhibitors,
pubmed-meshheading:19679424-Femoral Artery,
pubmed-meshheading:19679424-Humans,
pubmed-meshheading:19679424-Hyperemia,
pubmed-meshheading:19679424-Infusions, Intravenous,
pubmed-meshheading:19679424-Lower Extremity,
pubmed-meshheading:19679424-Nitric Oxide,
pubmed-meshheading:19679424-Nitric Oxide Synthase Type III,
pubmed-meshheading:19679424-Nitroglycerin,
pubmed-meshheading:19679424-Peripheral Vascular Diseases,
pubmed-meshheading:19679424-Popliteal Artery,
pubmed-meshheading:19679424-Regional Blood Flow,
pubmed-meshheading:19679424-Saphenous Vein,
pubmed-meshheading:19679424-Time Factors,
pubmed-meshheading:19679424-Treatment Outcome,
pubmed-meshheading:19679424-Ultrasonography, Doppler,
pubmed-meshheading:19679424-Vascular Patency,
pubmed-meshheading:19679424-Vasodilation,
pubmed-meshheading:19679424-Vasodilator Agents,
pubmed-meshheading:19679424-omega-N-Methylarginine
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pubmed:year |
2009
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pubmed:articleTitle |
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
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pubmed:affiliation |
Division of Vascular and Endovascular Surgery, University of California San Francisco, San Francisco, CA 94143-0222, USA. Christopher.Owens@ucsfmedctr.org
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pubmed:publicationType |
Journal Article
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