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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8681
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pubmed:dateCreated |
1990-2-20
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pubmed:abstractText |
Selective reduction was carried out in 46 multifetal pregnancies by means of potassium chloride injection into the pericardial region of the fetus. There were three indications for the procedure: to improve perinatal outcome and to increase the likelihood that a term infant would be born in a multifetal pregnancy (34 women); to allow the birth of a healthy infant without the birth of a congenitally abnormal coexisting fetus (8 women); and to preserve a singleton pregnancy when the woman would otherwise have the whole pregnancy terminated (4 women). Of the 80 fetuses left after reduction 75 (94%) have survived. In 3 cases ultrasound scanning showed cardiac activity in the injected fetus 20-30 min after the initial injection despite 2 min of asystole immediately after the injection; repeated injection, carried out the same day, led to fetal death in all 3 cases. Selective reduction of multifetal pregnancies for the three indications described is an ethically justifiable option for the management of multifetal pregnancy, to which there are no public policy obstacles.
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pubmed:keyword | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
335
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
90-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1967427-Congenital Abnormalities,
pubmed-meshheading:1967427-Ethics, Medical,
pubmed-meshheading:1967427-Evaluation Studies as Topic,
pubmed-meshheading:1967427-Female,
pubmed-meshheading:1967427-Fetal Death,
pubmed-meshheading:1967427-Fetal Diseases,
pubmed-meshheading:1967427-Fetal Heart,
pubmed-meshheading:1967427-Gestational Age,
pubmed-meshheading:1967427-Health Policy,
pubmed-meshheading:1967427-Humans,
pubmed-meshheading:1967427-Infant, Newborn,
pubmed-meshheading:1967427-Injections,
pubmed-meshheading:1967427-Patient Advocacy,
pubmed-meshheading:1967427-Potassium Chloride,
pubmed-meshheading:1967427-Pregnancy,
pubmed-meshheading:1967427-Pregnancy, Multiple,
pubmed-meshheading:1967427-Ultrasonography,
pubmed-meshheading:1967427-United States
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pubmed:year |
1990
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pubmed:articleTitle |
Selective reduction of multifetal pregnancies.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
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pubmed:publicationType |
Journal Article
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