Linked Life Data

1966467

Source:http://linkedlifedata.com/resource/pubmed/id/1966467

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1991-10-9
pubmed:abstractText
42 persons with normal blood pressure were studied. Only 31 of them were smokers. We did not find any differences in the basal blood pressure, heart rate, ACTH nor cortisol levels, but there were significant differences in the levels of biological markers of tobacco (cotinine and nicotine). When the smokers were induced to smoke 2 cigarettes which had 2.2 mg of nicotine, we observed an increase in the diastolic and systolic blood pressure as well as the heart rate, plasma levels of ACTH (basal: 21.61 +/- 12.52, 10 minutes: 28.06 +/- 21.01, p less than 0.05; 20 minutes: 26.06 +/- 18.56 ng/ml) and cortisol (basal: 14.56 +/- 3.84; 10 minutes: 14.60 +/- 4.7; 20 minutes: 16.55 +/- 6.61 ug/dl, p less than 0.01). At the same time, the nicotine and cotinine levels were significantly higher (p less than 0.0001) and correlated. Our results suggest that apart from the adrenergic response to tobacco exposure, nicotine can produce other hormonal changes which affect the regulating systems of blood pressure. Nicotine and cotinine are the election biological markers to monitor the response to passive or active tobacco smoke inhalation.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0212-7199
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
340-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Tobacco and arterial pressure (I.). The hormonal changes in a model of acute nicotine overload].
pubmed:affiliation
Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract