Source:http://linkedlifedata.com/resource/pubmed/id/19662146
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2009-8-7
|
pubmed:abstractText |
(11)C-labeled carbamates can be obtained in a three-component coupling reaction of primary or secondary amines with CO(2) and (11)C-methylation reagents. [(11)C]Methyl-triflate mediated methylation of carbamino adducts provides the corresponding (11)C-labeled carbamate groups in excellent yields under mild conditions (temperatures </= 40 degrees C, 2 min reaction time). The utility of the method has been demonstrated by a highly efficient radiosynthesis of [(11)C]GR103545.
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-10405772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-10628552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-11430069,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-11786275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-15750163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-18048446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19662146-7737460
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
|
pubmed:issn |
1874-1045
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
72-4
|
pubmed:year |
2008
|
pubmed:articleTitle |
A New Method for Radiosynthesis of C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [C]GR103545.
|
pubmed:affiliation |
Department of Chemistry, University of Oslo, Norway.
|
pubmed:publicationType |
Journal Article
|