rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2009-8-7
|
pubmed:abstractText |
Plasmacytoid dendritic cells (PDCs) infiltrating solid tumor tissues and draining lymph nodes of head and neck squamous cell carcinoma (HNSCC) show an impaired immune response. Immunosuppressive cytokines secreted by HNSCC have been recognized to account for reduced interferon-alpha (IFN-alpha) production, whereas the influence on PDC migration has not yet been investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1791-7530
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3019-25
|
pubmed:meshHeading |
pubmed-meshheading:19661310-Carcinoma, Squamous Cell,
pubmed-meshheading:19661310-Cell Movement,
pubmed-meshheading:19661310-Chemokine CCL4,
pubmed-meshheading:19661310-Chemokine CXCL12,
pubmed-meshheading:19661310-Dendritic Cells,
pubmed-meshheading:19661310-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19661310-Flow Cytometry,
pubmed-meshheading:19661310-Head and Neck Neoplasms,
pubmed-meshheading:19661310-Humans,
pubmed-meshheading:19661310-Interferon-alpha,
pubmed-meshheading:19661310-Oligodeoxyribonucleotides,
pubmed-meshheading:19661310-Receptors, CCR5,
pubmed-meshheading:19661310-Receptors, CXCR4,
pubmed-meshheading:19661310-Tumor Cells, Cultured
|
pubmed:year |
2009
|
pubmed:articleTitle |
Effect of head and neck cancer supernatant and CpG-oligonucleotides on migration and IFN-alpha production of plasmacytoid dendritic cells.
|
pubmed:affiliation |
Department of Otorhinolaryngology, University of Schleswig-Holstein Campus Lübeck, 23538 Lübeck, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|