19660006

Source:http://linkedlifedata.com/resource/pubmed/id/19660006

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0016229, umls-concept:C0017431, umls-concept:C0025519, umls-concept:C0057223, umls-concept:C0392747, umls-concept:C1280500, umls-concept:C1314939, umls-concept:C1332830
pubmed:issue	1
pubmed:dateCreated	2009-8-7
pubmed:abstractText	The aim of this study was to clarify the effects of CYP2D6 genotype on age-related change in flecainide metabolism in patients with supraventricular tachyarrhythmias. An in vitro study using microsomes was performed to identify other CYPs responsible for age-related change in flecainide metabolism.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Arrhythmia Agents, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP1A2, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP2D6, http://linkedlifedata.com/resource/pubmed/chemical/Flecainide
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1365-2125
pubmed:author	pubmed-author:AonumaKazutakaK, pubmed-author:DokiKosukeK, pubmed-author:HommaMasatoM, pubmed-author:KohdaYukinaoY, pubmed-author:KugaKeisukeK
pubmed:issnType	Electronic
pubmed:volume	68
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	89-96
pubmed:dateRevised	2010-9-27
pubmed:meshHeading	pubmed-meshheading:19660006-Adult, pubmed-meshheading:19660006-Age Factors, pubmed-meshheading:19660006-Aged, pubmed-meshheading:19660006-Aged, 80 and over, pubmed-meshheading:19660006-Anti-Arrhythmia Agents, pubmed-meshheading:19660006-Cytochrome P-450 CYP1A2, pubmed-meshheading:19660006-Cytochrome P-450 CYP2D6, pubmed-meshheading:19660006-Female, pubmed-meshheading:19660006-Flecainide, pubmed-meshheading:19660006-Genotype, pubmed-meshheading:19660006-Humans, pubmed-meshheading:19660006-Male, pubmed-meshheading:19660006-Middle Aged, pubmed-meshheading:19660006-Tachycardia, Supraventricular, pubmed-meshheading:19660006-Young Adult
pubmed:year	2009
pubmed:articleTitle	Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism.
pubmed:affiliation	Department of Pharmaceutical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't