Linked Life Data

1965886

Source:http://linkedlifedata.com/resource/pubmed/id/1965886

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-7-29
pubmed:abstractText
A method is described for detection of nonoxynol in condoms, based on methanol-water extraction followed by reverse-phase high-performance liquid chromatography. Using this method, we found that approximately 50% of the nonionic surfactant lubricant nonoxynol migrated into elastomers (rubber latex), resulting in a concentration of nonoxynol insufficient to inhibit human immunodeficiency virus (HIV) (less than 0.05%). In order to minimize the risk of sexual transmission of HIV, and to ensure spermicidal effect and optimal rubber properties, the concentration of nonoxynol in condoms, therefore, should either be increased, or nonoxynol should be packed separately. Further studies are needed to clarify and determine the solubility and migration of nonoxynols into elastomers.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0956-4624
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
346-8
pubmed:dateRevised
2001-11-26
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Evaluation of the amount of nonoxynol available in condoms for the inhibition of HIV using a method based on HPLC.
pubmed:affiliation
Department of Gastroenterology, Bispebjerg Hospital, University of Copenhagen, Denmark.
pubmed:publicationType
Journal Article