pubmed-article:19657750 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0349640 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0243095 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C1425194 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C1548702 | lld:lifeskim |
pubmed-article:19657750 | lifeskim:mentions | umls-concept:C1882911 | lld:lifeskim |
pubmed-article:19657750 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:19657750 | pubmed:dateCreated | 2010-8-20 | lld:pubmed |
pubmed-article:19657750 | pubmed:abstractText | Atypical chronic myeloid leukaemia (aCML) belongs to the myeloproliferative/myelodysplastic category of haematological disease. Main characteristics are marked dysgranulopoiesis, bone marrow dysfunction and the failure to demonstrate the presence of the Philadelphia chromosome or BCR/ABL fusion gene normally associated with CML t(9;22)(q34;q11). It carries a poor prognosis with limited therapeutic options available. Most cases of aCML have one or more karyotypic abnormalities. We highlight a clinical presentation of aCML associated with an acquired reciprocal whole-arm translocation (WAT), t(X;12)(p10;p10), which to our knowledge has not yet been described. We also discuss how such a translocation might lead to tumorigenesis. | lld:pubmed |
pubmed-article:19657750 | pubmed:language | eng | lld:pubmed |
pubmed-article:19657750 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19657750 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:19657750 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19657750 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19657750 | pubmed:month | Sep | lld:pubmed |
pubmed-article:19657750 | pubmed:issn | 1559-131X | lld:pubmed |
pubmed-article:19657750 | pubmed:author | pubmed-author:HamiltonJJ | lld:pubmed |
pubmed-article:19657750 | pubmed:author | pubmed-author:McMullinM FMF | lld:pubmed |
pubmed-article:19657750 | pubmed:author | pubmed-author:HumphreysM... | lld:pubmed |
pubmed-article:19657750 | pubmed:author | pubmed-author:ElderP TPT | lld:pubmed |
pubmed-article:19657750 | pubmed:author | pubmed-author:McGrattanPP | lld:pubmed |
pubmed-article:19657750 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:19657750 | pubmed:volume | 27 | lld:pubmed |
pubmed-article:19657750 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19657750 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19657750 | pubmed:pagination | 760-2 | lld:pubmed |
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pubmed-article:19657750 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:19657750 | pubmed:articleTitle | The finding of a reciprocal whole-arm translocation t(X;12)(p10;p10) in association with atypical chronic myeloid leukaemia. | lld:pubmed |
pubmed-article:19657750 | pubmed:affiliation | Department of Haematology, Belfast City Hospital, Belfast Health and Social Care Trust, Belfast, BT9-7AB, UK. patrickelder@doctors.org.uk | lld:pubmed |
pubmed-article:19657750 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19657750 | pubmed:publicationType | Case Reports | lld:pubmed |