Linked Life Data

19656712

Source:http://linkedlifedata.com/resource/pubmed/id/19656712

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-3-24
pubmed:abstractText
HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated with HAART results in dramatic clinical benefits, but this restoration of immunity may result in immunopathological reactions. The immune reconstitution inflammatory syndrome can result in fever, nodal enlargement, and worsening pulmonary infiltrates observed on a chest radiograph, with or without recurrent respiratory symptoms. Several other manifestations have also been described. As a consequence, the use of HAART might not be appropriate during the first weeks of anti-TB therapy in HIV-infected patients. In this review, we summarize the incidence, clinical presentations, and potential mechanisms of these conditions and we describe therapeutic methods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1878-3511
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e283-91
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: a systematic review.
pubmed:affiliation
Infectious Diseases Division, San Giuseppe Moscati Hospital, Avellino, Italy. sebastianoleone@yahoo.it
pubmed:publicationType
Journal Article, Review