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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-7-11
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pubmed:abstractText |
Previous research on the aerial parts of Calendula arvensis led to the isolation of the epicubebol glycoside 1 and of the sesquiterpene glycosides 2-5 based on the alloaromadendrane skeleton. A further investigation has revealed two new glycosides, 6 and 7, derived from the same sesquiterpene, the structures of which were elucidated by spectral studies. Furthermore a series of antiviral tests has been performed on glycosides 1-7 by examining their ability to interfere with rhinovirus 1B and vesicular stomatitis virus infection in vitro. Only glycoside 1 slightly reduced rhinovirus multiplication. All the compounds were able to inhibit vesicular stomatitis virus infection, 1 and 2 being the most effective.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
830-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1965654-Animals,
pubmed-meshheading:1965654-Antiviral Agents,
pubmed-meshheading:1965654-Chick Embryo,
pubmed-meshheading:1965654-Glycosides,
pubmed-meshheading:1965654-HeLa Cells,
pubmed-meshheading:1965654-Humans,
pubmed-meshheading:1965654-Magnetic Resonance Spectroscopy,
pubmed-meshheading:1965654-Molecular Structure,
pubmed-meshheading:1965654-Plants, Medicinal,
pubmed-meshheading:1965654-Rhinovirus,
pubmed-meshheading:1965654-Sesquiterpenes,
pubmed-meshheading:1965654-Vesicular stomatitis Indiana virus
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pubmed:articleTitle |
Structure and in vitro antiviral activity of sesquiterpene glycosides from Calendula arvensis.
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pubmed:affiliation |
Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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