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rdf:type |
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lifeskim:mentions |
umls-concept:C0013855,
umls-concept:C0017431,
umls-concept:C0020205,
umls-concept:C0021344,
umls-concept:C0022885,
umls-concept:C0032520,
umls-concept:C0036849,
umls-concept:C0039593,
umls-concept:C0201679,
umls-concept:C0205064,
umls-concept:C0205314,
umls-concept:C0332257,
umls-concept:C0370003,
umls-concept:C0679622,
umls-concept:C0999806,
umls-concept:C1442518,
umls-concept:C1510438,
umls-concept:C1511790,
umls-concept:C1552652,
umls-concept:C1552685,
umls-concept:C1624252,
umls-concept:C1705195,
umls-concept:C1707455
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pubmed:issue |
4
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pubmed:dateCreated |
2009-8-5
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pubmed:abstractText |
The aim of this study was to compare the novel human papillomavirus (HPV) detection method, the HPV 4 Auto-capillary Electrophoresis (ACE) test with the hybrid capture (HC) 2 assay for the detection of high-risk HPVs. In addition, we compared the HPV 4 ACE test with the polymerase chain reaction HPV Typing Set test for the detection of HPV 16 and HPV 18 genotypes. One hundred ninety-nine cervical swab samples obtained from women with previous abnormal Pap smears were subjected to testing with the three HPV tests. The HPV 4 ACE test and the HC 2 assay showed substantial agreement for detection of high-risk HPVs (85.4%, kappa=0.71). The HPV 4 ACE test also showed substantial agreement with the PCR HPV Typing Set test in the detection of HPV 16 and HP V 18 genotypes (89.9%, kappa=0.65). In correlation with cytologic results, the sensitivities and specificities of the HPV 4 ACE test and HC 2 assay were 92.9% vs. 92.9% and 48.1% vs. 50.8%, respectively, when high-grade squamous intraepithelial lesions were regarded as abnormal cytologies. The novel HPV 4 ACE test is a valuable tool for the detection of high-risk HPVs and for genotyping of HPV 16 and HPV 18.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-10451482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-10618116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-11865004,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-11880448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-11919208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-11992586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-12467785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-12556961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-1330933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-15780805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-15837742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-16030304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-16757611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-17287288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-17405118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-17494721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-18417407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-1851805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-18716224,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-18835300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-7791229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-9041439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-9049358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-9738060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19654936-9846964
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1598-6357
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19654936-Cervix Uteri,
pubmed-meshheading:19654936-DNA, Viral,
pubmed-meshheading:19654936-Electrophoresis, Capillary,
pubmed-meshheading:19654936-Female,
pubmed-meshheading:19654936-Gammapapillomavirus,
pubmed-meshheading:19654936-Genotype,
pubmed-meshheading:19654936-Human papillomavirus 16,
pubmed-meshheading:19654936-Human papillomavirus 18,
pubmed-meshheading:19654936-Humans,
pubmed-meshheading:19654936-Nucleic Acid Hybridization,
pubmed-meshheading:19654936-Polymerase Chain Reaction,
pubmed-meshheading:19654936-Reagent Kits, Diagnostic,
pubmed-meshheading:19654936-Vaginal Smears
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pubmed:year |
2009
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pubmed:articleTitle |
Comparison of the novel human papillomavirus 4 auto-capillary electrophoresis test with the hybrid capture 2 assay and with the PCR HPV typing set test in the detection of high-risk HPV including HPV 16 and 18 genotypes in cervical specimens.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Guro Hospital, College of Medicine, Korea University, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Comparative Study
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