Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-9-18
pubmed:abstractText
Neurotensin (NT) is a neuropeptide with antinociceptive effects that are mediated through NT receptors, of which there are three known subtypes (NTS1, NTS2, and NTS3). Morphine is a mu-opioid receptor agonist commonly used for pain treatment but is associated with side effects that can be serious. We hypothesize that selective NT receptor agonists may represent a novel class of analgesics and their use in conjunction with morphine will have synergistic properties which may reduce the dose of morphine administered and its side effects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1872-6240
pubmed:author
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
1294
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
22-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
NT69L, a novel analgesic, shows synergy with morphine.
pubmed:affiliation
Neuropsychopharmacology Laboratory, Mayo Foundation for Medical Education and Research, Jacksonville, Florida, USA. boules.mona@mayo.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't