rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2009-8-3
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pubmed:abstractText |
The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patient data analysis of efficacy and tolerability in acute uncomplicated falciparum malaria, from seven published randomized clinical trials conducted in Africa and South East Asia using a predefined in-vivo protocol. Comparator drugs were mefloquine-artesunate (MAS3) in Thailand, Myanmar, Laos and Cambodia; artemether-lumefantrine in Uganda; and amodiaquine+sulfadoxine-pyrimethamine and artesunate+amodiaquine in Rwanda.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-11440947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-12125116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-12958120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-14723988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-14998421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-15482401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-15499533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-15610051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-16028147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-16766006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-16798391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-16903879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17123974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17187673,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17300633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17330781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17525792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17822532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-17846129,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-18471066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-18497415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-18840754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-19017387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-19064624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-3260147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-8642959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-9657512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19649267-9988316
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AshleyElizabeth AEA,
pubmed-author:D'AlessandroUmbertoU,
pubmed-author:DorseyGrantG,
pubmed-author:JanssensBartB,
pubmed-author:KaremaCorineC,
pubmed-author:MayxayMayfongM,
pubmed-author:NewtonPaulP,
pubmed-author:NostenFrançoisF,
pubmed-author:SinghasivanonPratapP,
pubmed-author:SmithuisFrankF,
pubmed-author:StepniewskaKasiaK,
pubmed-author:WhiteNicholas JNJ,
pubmed-author:ZwangJulienJ
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pubmed:issnType |
Electronic
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e6358
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19649267-Adolescent,
pubmed-meshheading:19649267-Adult,
pubmed-meshheading:19649267-Aged,
pubmed-meshheading:19649267-Antimalarials,
pubmed-meshheading:19649267-Artemisinins,
pubmed-meshheading:19649267-Child,
pubmed-meshheading:19649267-Child, Preschool,
pubmed-meshheading:19649267-Female,
pubmed-meshheading:19649267-Humans,
pubmed-meshheading:19649267-Infant,
pubmed-meshheading:19649267-Malaria, Falciparum,
pubmed-meshheading:19649267-Male,
pubmed-meshheading:19649267-Middle Aged,
pubmed-meshheading:19649267-Prospective Studies,
pubmed-meshheading:19649267-Quinolines,
pubmed-meshheading:19649267-Randomized Controlled Trials as Topic
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pubmed:year |
2009
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pubmed:articleTitle |
Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis.
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pubmed:affiliation |
Shoklo Malaria Research Unit, Mae Sot, Thailand.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|