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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-12
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pubmed:abstractText |
C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells. To validate the potential of this receptor as a therapeutic target in acute myeloid leukemia, we generated a series of monoclonal antibodies against the extracellular domain of C-type lectin-like molecule-1 and used them to extend the expression profile analysis of acute myeloid leukemia cells and to select cytotoxic monoclonal antibodies against acute myeloid leukemia cells in preclinical models.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-10910899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-11320212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-12685823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-12941951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-1458463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-14601078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-14739280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-14751265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15238421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15454492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15548716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15728446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15789036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-15956254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-16239426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-16412015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-16971805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-17456053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-17530016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-17609428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-17658267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-17786921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-18452067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-18922830,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-19440216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-7680959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19648166-9203414
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1592-8721
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-8
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pubmed:meshHeading |
pubmed-meshheading:19648166-Animals,
pubmed-meshheading:19648166-Antibodies, Monoclonal,
pubmed-meshheading:19648166-CHO Cells,
pubmed-meshheading:19648166-Cell Line,
pubmed-meshheading:19648166-Cricetinae,
pubmed-meshheading:19648166-Cricetulus,
pubmed-meshheading:19648166-HL-60 Cells,
pubmed-meshheading:19648166-Humans,
pubmed-meshheading:19648166-Immunotherapy,
pubmed-meshheading:19648166-Lectins, C-Type,
pubmed-meshheading:19648166-Leukemia, Myeloid, Acute,
pubmed-meshheading:19648166-Mice,
pubmed-meshheading:19648166-Mice, Inbred BALB C,
pubmed-meshheading:19648166-Mice, SCID,
pubmed-meshheading:19648166-Protein Transport,
pubmed-meshheading:19648166-Xenograft Model Antitumor Assays
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pubmed:year |
2010
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pubmed:articleTitle |
Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia.
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pubmed:affiliation |
Department of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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