Linked Life Data

19646253

Source:http://linkedlifedata.com/resource/pubmed/id/19646253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-8-31
pubmed:abstractText
Functional genomics tools provide researchers with the ability to apply high-throughput techniques to determine the function and interaction of a diverse range of genes. Mutagenized plant populations are one such resource that facilitate gene characterisation. They allow complex physiological responses to be correlated with the expression of single genes in planta, through either reverse genetics where target genes are mutagenized to assay the affect, or through forward genetics where populations of mutant lines are screened to identify those whose phenotype diverges from wild type for a particular trait. One limitation of these types of populations is the prevalence of gene redundancy within plant genomes, which can mask the affect of individual genes. Activation or enhancer populations, which not only provide knock-out but also dominant activation mutations, can facilitate the study of such genes.
pubmed:commentsCorrections
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pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1471-2229
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
101
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
An archived activation tagged population of Arabidopsis thaliana to facilitate forward genetics approaches.
pubmed:affiliation
Agriculture and Agri-Food Canada, Saskatoon Research Centre, 107 Science Place, Saskatoon S7N0X2, Canada. Steve.Robinson@agr.gc.ca
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't