Linked Life Data

1964510

Source:http://linkedlifedata.com/resource/pubmed/id/1964510

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-5-9
pubmed:abstractText
The effects of calcium ion on the contractile response of gallbladder muscle strip (GBMS) in guinea pigs to acetylcholine, carbachol and caerulein were investigated by method of isotonic contraction and by RIA of cGMP and cAMP in the tissue. It was shown that the contractile response of GBMS to these agonists was stronger in Krebs solution than that in the calcium-free solution. In calcium-free solution, EDTA-zero calcium solution or verapamil-Krebs solution, the contractile response of GBMD was decreased to about 30% of the control (P less than 0.01). Verapamil significantly decreased carbachol induced enhancement of cGMP and cAMP of gallbladder tissue (P less than 0.01 or 0.05). The results suggest that both extra-and intra- cellular calcium take part in the contractile response of GBMS to agonists.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0371-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
284-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Effects of calcium ion on contractile response of guinea-pig gallbladder muscle strip to agonists].
pubmed:affiliation
Department of Physiology, Dalian Medical College.
pubmed:publicationType
Journal Article, In Vitro, English Abstract