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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-7-31
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pubmed:abstractText |
Chemokine receptor 5 (CCR-5) plays a central role in allograft rejection. CCR-5Delta32 mutation results in a non-functioning receptor. Homozygous CCR-5Delta32 patients show a significantly improved kidney graft survival rate compared to CCR-5 wild-type patients. Similar correlations between the CCR-5Delta32 genotype and acute rejection or graft survival rate were shown for heart, lung and islet cell transplantation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1425-9524
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-44
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pubmed:meshHeading |
pubmed-meshheading:19644158-Acute Disease,
pubmed-meshheading:19644158-Adult,
pubmed-meshheading:19644158-Base Sequence,
pubmed-meshheading:19644158-DNA Primers,
pubmed-meshheading:19644158-Female,
pubmed-meshheading:19644158-Genotype,
pubmed-meshheading:19644158-Graft Rejection,
pubmed-meshheading:19644158-Graft Survival,
pubmed-meshheading:19644158-Heterozygote,
pubmed-meshheading:19644158-Homozygote,
pubmed-meshheading:19644158-Humans,
pubmed-meshheading:19644158-Liver Transplantation,
pubmed-meshheading:19644158-Male,
pubmed-meshheading:19644158-Middle Aged,
pubmed-meshheading:19644158-Mutation,
pubmed-meshheading:19644158-Prospective Studies,
pubmed-meshheading:19644158-Receptors, CCR5,
pubmed-meshheading:19644158-Risk Factors,
pubmed-meshheading:19644158-Sequence Deletion
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pubmed:articleTitle |
Chemokine receptor 5Delta32 mutation reduces the risk of acute rejection in liver transplantation.
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pubmed:affiliation |
University Medicine Berlin, Charite, General, Visceral and Transplantation Surgery, Berlin, Germany. christoph.heidenhain@charite.de
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pubmed:publicationType |
Journal Article
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