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pubmed-article:19637860pubmed:abstractTextAn efficient and flexible synthesis of poison-frog alkaloids 251O and trans-223B has been achieved by using for both alkaloids an enantiodivergent process starting from the common lactam 1. The relative stereochemistry of 251O and trans-223B was determined to be 7 (R = n-C(7)H(15), R' = n-Pr) and 14 by the present enantioselective synthesis.lld:pubmed
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pubmed-article:19637860pubmed:dateRevised2010-9-13lld:pubmed
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pubmed-article:19637860pubmed:articleTitleEfficient enantio- and diastereodivergent synthesis of poison-frog alkaloids 251O and trans-223B.lld:pubmed
pubmed-article:19637860pubmed:affiliationGraduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama 930-0194, Japan. toyooka@pha.u-toyama.ac.jplld:pubmed
pubmed-article:19637860pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19637860pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:19637860pubmed:publicationTypeResearch Support, N.I.H., Intramurallld:pubmed