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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-7-28
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pubmed:abstractText |
Rheb (Ras homologue enriched in brain) is a small GTPase that plays an important role in tuberous sclerosis. Here we present the backbone assignments of rRheb in its GDP-bound state. These assignments now provide a basis for the analysis of the interaction of rRheb with putative factors in order to elucidate the function of this GTPase and its role in the MAP kinase pathway of neuronal cells and in tuberous sclerosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1874-270X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-7
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pubmed:meshHeading |
pubmed-meshheading:19636822-Guanosine Diphosphate,
pubmed-meshheading:19636822-Humans,
pubmed-meshheading:19636822-MAP Kinase Signaling System,
pubmed-meshheading:19636822-Molecular Structure,
pubmed-meshheading:19636822-Monomeric GTP-Binding Proteins,
pubmed-meshheading:19636822-Neuropeptides,
pubmed-meshheading:19636822-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:19636822-Protein Binding,
pubmed-meshheading:19636822-Recombinant Proteins,
pubmed-meshheading:19636822-Tuberous Sclerosis
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pubmed:year |
2007
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pubmed:articleTitle |
Sequence-specific 1H, 13C, and 15N backbone assignment of the GTPase rRheb in its GDP-bound form.
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pubmed:affiliation |
Biomolecular NMR, Faculty of Chemistry and Biochemistry, Ruhr-University of Bochum, Bochum 44780, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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