19635193

Source:http://linkedlifedata.com/resource/pubmed/id/19635193

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013216, umls-concept:C0017638, umls-concept:C0025723, umls-concept:C0025831, umls-concept:C0086860, umls-concept:C1511790
pubmed:issue	6
pubmed:dateCreated	2009-7-28
pubmed:abstractText	Epigenetic silencing of the DNA repair gene, O6-methylguanine-DNA methyltransferase (MGMT), is associated with the therapeutic response to methylating agents. This study was to assess the value of detecting the promoter methylation of MGMT gene in chemotherapy for glioma.
pubmed:language	chi
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9424852
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Alkylating, http://linkedlifedata.com/resource/pubmed/chemical/Azacitidine, http://linkedlifedata.com/resource/pubmed/chemical/Dacarbazine, http://linkedlifedata.com/resource/pubmed/chemical/Nimustine, http://linkedlifedata.com/resource/pubmed/chemical/O(6)-Methylguanine-DNA..., http://linkedlifedata.com/resource/pubmed/chemical/decitabine, http://linkedlifedata.com/resource/pubmed/chemical/temozolomide
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1000-467X
pubmed:author	pubmed-author:GongFengF, pubmed-author:JiShou-PingSP, pubmed-author:LiAn-MingAM, pubmed-author:TaiJun-LiJL, pubmed-author:ZhangYang-PeiYP, pubmed-author:ZhengChang-QingCQ
pubmed:issnType	Print
pubmed:volume	28
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	575-80
pubmed:meshHeading	pubmed-meshheading:19635193-Adolescent, pubmed-meshheading:19635193-Adult, pubmed-meshheading:19635193-Aged, pubmed-meshheading:19635193-Antimetabolites, Antineoplastic, pubmed-meshheading:19635193-Antineoplastic Agents, Alkylating, pubmed-meshheading:19635193-Azacitidine, pubmed-meshheading:19635193-Brain Neoplasms, pubmed-meshheading:19635193-Cell Line, Tumor, pubmed-meshheading:19635193-CpG Islands, pubmed-meshheading:19635193-DNA Methylation, pubmed-meshheading:19635193-Dacarbazine, pubmed-meshheading:19635193-Drug Resistance, Neoplasm, pubmed-meshheading:19635193-Female, pubmed-meshheading:19635193-Follow-Up Studies, pubmed-meshheading:19635193-Glioma, pubmed-meshheading:19635193-Humans, pubmed-meshheading:19635193-Male, pubmed-meshheading:19635193-Middle Aged, pubmed-meshheading:19635193-Nimustine, pubmed-meshheading:19635193-O(6)-Methylguanine-DNA Methyltransferase, pubmed-meshheading:19635193-Promoter Regions, Genetic, pubmed-meshheading:19635193-Survival Rate, pubmed-meshheading:19635193-Young Adult
pubmed:year	2009
pubmed:articleTitle	[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
pubmed:affiliation	Department of Biochemistry and Molecular Biology, Institute of Transfusion Medicine, Academy of Military Medical Sciences, Beijing, 100850, P.R. China.
pubmed:publicationType	Journal Article, English Abstract, Research Support, Non-U.S. Gov't