Linked Life Data

19631386

Source:http://linkedlifedata.com/resource/pubmed/id/19631386

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-8-31
pubmed:abstractText
The condensation of 7-amino-4-methyl-coumarin (1) with a number of substituted salicylaldehydes yielded a series of Schiff bases (2a-2k) in good yields. Subsequent reaction of these ligands with copper(II) acetate yielded Cu(II) complexes (3a-3k) and some were characterised using X-ray crystallography. All of the free ligands and their metal complexes were tested for their anti-Candida activity. A number of the ligands and complexes exhibited anti-Candida activity comparable to that of the commercially available antifungal drugs, ketoconazole and Amphotericin B.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1873-3344
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1196-203
pubmed:dateRevised
2010-1-28
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity.
pubmed:affiliation
Department of Science, Institute of Technology Tallaght, Dublin, Ireland. bernie.creaven@it-tallaght.ie
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't