Linked Life Data

19631281

Source:http://linkedlifedata.com/resource/pubmed/id/19631281

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-2-22
pubmed:abstractText
Sox proteins are found in all metazoans and are active in many developmental processes. Their function as transcription factors is governed by their DNA-binding properties as much as by their interactions with other transcription factors and cofactors, and subject to modulation by posttranslational modifications. Although most Sox proteins predominantly function as transcriptional activators, there is also evidence for transcriptional repression and architectural roles. Further effects involve complex formation of Sox proteins with transcriptionally relevant factors off DNA. Sox proteins may be additionally active on the posttranscriptional level and are therefore remarkably versatile regulators of gene expression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1878-5875
pubmed:author
pubmed:copyrightInfo
Copyright 2009 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-90
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
All purpose Sox: The many roles of Sox proteins in gene expression.
pubmed:affiliation
Institut für Biochemie, Emil-Fischer-Zentrum, Universität Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany. m.wegner@biochem.uni-erlangen.de
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't