Linked Life Data

19631211

Source:http://linkedlifedata.com/resource/pubmed/id/19631211

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17
pubmed:dateCreated
2009-9-1
pubmed:abstractText
Transport of membranes and proteins in eukaryotic cells is mediated by vesicular carriers. Here we review the biogenesis and functions of COPI vesicles, carriers that operate in the early secretory pathway. We focus on mechanisms mediating coat recruitment, uptake of cargo, vesicle budding and fission, and finally dissociation of the coat. In this context, recent findings on the interplay between machinery and auxiliary proteins in COPI vesicle formation and function will be discussed. Specifically, we will weigh the pros and cons of recent data on roles of the small GTP binding protein Arf1, of Arf1GAPs, and lipids during COPI carrier formation.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1873-3468
pubmed:author
pubmed:issnType
Electronic
pubmed:day
3
pubmed:volume
583
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2701-9
pubmed:dateRevised
2009-12-3
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
The COPI system: molecular mechanisms and function.
pubmed:affiliation
Yale University School of Medicine, Department of Cell Biology, New Haven, CT 06520, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't