Source:http://linkedlifedata.com/resource/pubmed/id/19631027
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-7-27
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pubmed:abstractText |
Cardiovascular calcium deposition is associated with osteoporosis through various potential mechanisms involving molecular regulatory factors at the nanoscale level that govern skeletal bone and cardiovascular tissues. In this article, several possible mechanisms linking cardiovascular calcification and osteoporosis are discussed, including aging, tissue-specific responses to chronic inflammation, flow-limiting atherosclerosis of skeletal end arteries causing ischemic abnormalities in metabolism, shared endogenous regulatory factors that affect the two tissues in a reciprocal manner, and changes in a cysteine protease inhibitor, fetuin. Any or all of these factors and phenomena may contribute to the association.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1544-2241
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
42-6
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pubmed:meshHeading |
pubmed-meshheading:19631027-Aging,
pubmed-meshheading:19631027-Atherosclerosis,
pubmed-meshheading:19631027-Calcinosis,
pubmed-meshheading:19631027-Cardiovascular Diseases,
pubmed-meshheading:19631027-Humans,
pubmed-meshheading:19631027-Motor Activity,
pubmed-meshheading:19631027-Osteoporosis,
pubmed-meshheading:19631027-alpha-Fetoproteins
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pubmed:year |
2009
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pubmed:articleTitle |
Mechanisms linking osteoporosis with cardiovascular calcification.
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pubmed:affiliation |
Department of Medicine, BH-307 Center for Health Sciences, Los Angeles, CA 90095-1679, USA. Ldemer@mednet.ucla.edu
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pubmed:publicationType |
Journal Article
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