19630971

Source:http://linkedlifedata.com/resource/pubmed/id/19630971

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008059, umls-concept:C0013162, umls-concept:C0024534, umls-concept:C0024581, umls-concept:C0036043
pubmed:dateCreated	2009-8-11
pubmed:databankReference	http://linkedlifedata.com/resource/pubmed/xref/ClinicalTrials.gov/NCT00697164
pubmed:abstractText	Cerebral malaria carries an unacceptable case fatality rate in children despite timely and adequate chemotherapy. To improve the survival rate, adjunctive therapies previously tested mainly focused on the modulation of the inflammatory response, without definitive effect in humans. In this context, a new adjunctive strategy using a neuroprotective drug: erythropoietin (epoietin-beta, Epo) was proposed.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101139802
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials, http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations, http://linkedlifedata.com/resource/pubmed/chemical/Erythropoietin, http://linkedlifedata.com/resource/pubmed/chemical/Quinine, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/epoetin beta
pubmed:status	MEDLINE
pubmed:issn	1475-2875
pubmed:author	pubmed-author:BambaKaridiatouK, pubmed-author:BarryAbdoulayeA, pubmed-author:BienvenuAnne-LiseAL, pubmed-author:DiarraElisabethE, pubmed-author:DjimdéAbdoulayeA, pubmed-author:DoumboOgobara KOK, pubmed-author:KonateSalimataS, pubmed-author:PicotStéphaneS, pubmed-author:SissokoSibiriS
pubmed:issnType	Electronic
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	169
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:19630971-Antimalarials, pubmed-meshheading:19630971-Child, pubmed-meshheading:19630971-Child, Preschool, pubmed-meshheading:19630971-Drug Combinations, pubmed-meshheading:19630971-Erythropoietin, pubmed-meshheading:19630971-Female, pubmed-meshheading:19630971-Humans, pubmed-meshheading:19630971-Infant, pubmed-meshheading:19630971-Malaria, Cerebral, pubmed-meshheading:19630971-Male, pubmed-meshheading:19630971-Mali, pubmed-meshheading:19630971-Quinine, pubmed-meshheading:19630971-Recombinant Proteins
pubmed:year	2009
pubmed:articleTitle	Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali.
pubmed:affiliation	Malaria Research Unit, EA 4170, University Lyon 1, Faculty of Medicine, Lyon, France. picot@sante.univ-lyon1.fr
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't