Linked Life Data

19630382

Source:http://linkedlifedata.com/resource/pubmed/id/19630382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2009-9-1
pubmed:abstractText
The intramolecular variant of the homo-[3 + 2]-dipolar cycloaddition of nitrones (generated in situ from an aldehyde and a hydroxylamine) with donor-acceptor cyclopropanes allows for the efficient synthesis of bridged tetrahydro-1,2-oxazines. This domino sequence produces adducts amenable to reductive N-O bond cleavage producing cis-1,4-aminocyclohexanols in excellent yields.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1523-7052
pubmed:author
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3694-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Domino synthesis of bridged bicyclic tetrahydro-1,2-oxazines: access to stereodefined 4-aminocyclohexanols.
pubmed:affiliation
Department of Chemistry, The University of Western Ontario, London, Ontario, Canada N6A 5B7.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't