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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-11-20
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pubmed:abstractText |
Dietary linoleic acid, an n-6 polyunsaturated fatty acid, is metabolised to arachidonic acid, a component of colonocyte membranes. Metabolites of arachidonic acid have pro-inflammatory properties and are increased in the mucosa of patients with ulcerative colitis. The aim of this investigation was to conduct the first prospective cohort study investigating if a high dietary intake of linoleic acid increases the risk of developing incident ulcerative colitis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:BerglundGG,
pubmed-author:BergmannM MMM,
pubmed-author:BinghamSS,
pubmed-author:DasN KNK,
pubmed-author:EadeN RNR,
pubmed-author:HagglundGG,
pubmed-author:HallmansGG,
pubmed-author:HaraRR,
pubmed-author:IBD in EPIC Study Investigators,
pubmed-author:KennedyHH,
pubmed-author:KhawK-TKT,
pubmed-author:LindgrenSS,
pubmed-author:LinseisenJJ,
pubmed-author:NagelGG,
pubmed-author:OvervadKK,
pubmed-author:PallaLL,
pubmed-author:PalmqvistRR,
pubmed-author:RiboliEE,
pubmed-author:SjodinHH,
pubmed-author:TjonnelandAA
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1606-11
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pubmed:meshHeading |
pubmed-meshheading:19628674-Adult,
pubmed-meshheading:19628674-Aged,
pubmed-meshheading:19628674-Colitis, Ulcerative,
pubmed-meshheading:19628674-Diet,
pubmed-meshheading:19628674-Dietary Fats, Unsaturated,
pubmed-meshheading:19628674-Epidemiologic Methods,
pubmed-meshheading:19628674-Europe,
pubmed-meshheading:19628674-Female,
pubmed-meshheading:19628674-Food Habits,
pubmed-meshheading:19628674-Humans,
pubmed-meshheading:19628674-Linoleic Acid,
pubmed-meshheading:19628674-Male,
pubmed-meshheading:19628674-Middle Aged
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pubmed:year |
2009
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pubmed:articleTitle |
Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study.
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pubmed:affiliation |
University of East Anglia, Norwich, NR4 7TJ, UK. a.hart@uea.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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