Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-7-24
pubmed:abstractText
Many fabrication routes used to process biomaterials result in residual stresses. The presence of residual stress can cause failure or even change the dissolution rates of many materials, in particular biomaterials that are designed to be resorbed. Stored strain energy can add extra thermodynamic driving force for dissolution and result in varied dissolution rates depending on the sign of the stress. This work describes in vitro testing in phosphate buffer solution after micro-indenting the surface of bioactive glass 45S5 discs with varying loads. Indentation and fracture characteristics of the bioactive glass are discussed. Local dissolution and morphology of mineral deposits at the surface were analyzed by scanning electron microscopy to determine the effects of local residual stresses on bioactivity. It was found that the compressive stress field surrounding indents (above a threshold indentation load) slowed the dissolution of the bioactive glass significantly.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1878-0180
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-51
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
In vitro bioactivity of 45S5 bioactive glass as a function of indentation load.
pubmed:affiliation
Chemical and Materials Engineering Department, University of Kentucky, Lexington, 40506-046, USA. jnychka@ualberta.ca
pubmed:publicationType
Journal Article