rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-7-23
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pubmed:abstractText |
Histone deacetylase inhibitors (HDACi) exert antitumor effects through the induction of apoptosis. This study was to investigate the effects of HDACi on survivin gene expression, cell proliferation and apoptosis in human myeloma cell line U266.
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pubmed:language |
chi
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BIRC5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Benzamides,
http://linkedlifedata.com/resource/pubmed/chemical/CDK4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase 4,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Histones,
http://linkedlifedata.com/resource/pubmed/chemical/Inhibitor of Apoptosis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/N-(2-aminophenyl)-4-(N-(pyridin-3-yl...,
http://linkedlifedata.com/resource/pubmed/chemical/Poly(ADP-ribose) Polymerases,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1000-467X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
466-71
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pubmed:meshHeading |
pubmed-meshheading:19624872-Acetylation,
pubmed-meshheading:19624872-Apoptosis,
pubmed-meshheading:19624872-Benzamides,
pubmed-meshheading:19624872-Caspase 3,
pubmed-meshheading:19624872-Cell Cycle,
pubmed-meshheading:19624872-Cell Line, Tumor,
pubmed-meshheading:19624872-Cell Proliferation,
pubmed-meshheading:19624872-Cyclin-Dependent Kinase 4,
pubmed-meshheading:19624872-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:19624872-Dose-Response Relationship, Drug,
pubmed-meshheading:19624872-Down-Regulation,
pubmed-meshheading:19624872-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19624872-Histone Deacetylase Inhibitors,
pubmed-meshheading:19624872-Histones,
pubmed-meshheading:19624872-Humans,
pubmed-meshheading:19624872-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:19624872-Multiple Myeloma,
pubmed-meshheading:19624872-Poly(ADP-ribose) Polymerases,
pubmed-meshheading:19624872-Pyridines
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pubmed:year |
2009
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pubmed:articleTitle |
[MS-275, a histone deacetylase inhibitor, induces apoptosis and alters survivin gene expression in human myeloma cell line U266].
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pubmed:affiliation |
Department of Hematology, First Affiliated Hospital of General Hospital of PLA, Beijing, China. mashixuan@163.com
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pubmed:publicationType |
Journal Article,
English Abstract
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