19622686

Source:http://linkedlifedata.com/resource/pubmed/id/19622686

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004781, umls-concept:C0007610, umls-concept:C0014556, umls-concept:C0205160, umls-concept:C0333641, umls-concept:C1457887
pubmed:issue	2
pubmed:dateCreated	2009-7-22
pubmed:abstractText	Recent work has identified the presence of negative symptoms in a subset of temporal lobe epilepsy (TLE) patients. The authors hypothesized that negative symptoms in TLE are associated with disruption in the mesolimbic system. Basal ganglia and anterior cingulate region of interest volumes were compared between 22 TLE patients with negative symptoms, 22 TLE patients without negative symptoms, and 22 comparison subjects. The negative symptom group showed significantly reduced volumes in the putamen and globus pallidus. It appears that these structures within the broader mesolimbic system contribute to the phenomenon of negative symptoms in TLE.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/2R01 37738, http://linkedlifedata.com/resource/pubmed/grant/M01 RR 03186, http://linkedlifedata.com/resource/pubmed/grant/M01 RR003186-190296, http://linkedlifedata.com/resource/pubmed/grant/R01 NS037738-06
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8911344
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	1545-7222
pubmed:author	pubmed-author:GearyElizabeth KEK, pubmed-author:HermannBruceB, pubmed-author:SeidenbergMichaelM
pubmed:issnType	Electronic
pubmed:volume	21
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	152-9
pubmed:dateRevised	2010-9-27
pubmed:meshHeading	pubmed-meshheading:19622686-Adult, pubmed-meshheading:19622686-Affective Symptoms, pubmed-meshheading:19622686-Atrophy, pubmed-meshheading:19622686-Basal Ganglia, pubmed-meshheading:19622686-Epilepsy, Temporal Lobe, pubmed-meshheading:19622686-Female, pubmed-meshheading:19622686-Humans, pubmed-meshheading:19622686-Magnetic Resonance Imaging, pubmed-meshheading:19622686-Male, pubmed-meshheading:19622686-Middle Aged, pubmed-meshheading:19622686-Young Adult
pubmed:year	2009
pubmed:articleTitle	Atrophy of basal ganglia nuclei and negative symptoms in temporal lobe epilepsy.
pubmed:affiliation	Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, USA. ekgeary@uic.edu
pubmed:publicationType	Journal Article, Comparative Study, Research Support, N.I.H., Extramural