Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2009-9-14
pubmed:abstractText
Chronic inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD). It is influenced by both environmental and genetic factors. CD40 signaling has been linked to pathogenic processes of chronic inflammatory diseases. After interaction with its ligand CD154 (CD40L), CD40 induces a broad variety of chronic inflammatory responses, inducing the release of inflammatory mediators. We investigated whether a CD40 gene (-1C/T) single nucleotide polymorphism (SNP) is associated with COPD in a Chinese population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1873-3492
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
408
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
56-9
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Association of CD40 -1C/T polymorphism in the 5'-untranslated region and chronic obstructive pulmonary disease.
pubmed:affiliation
Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't