Linked Life Data

19621368

Source:http://linkedlifedata.com/resource/pubmed/id/19621368

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-1-25
pubmed:abstractText
A coherent and meaningful percept of the world is essential for human nature. Consequently, much speculation has focused on how this is achieved in the brain. It is thought that all conscious experiences have reference to the self. Self-reference may either be minimal or extended, i.e., autonoetic. In minimal self-reference subjective experiences are self-aware in the weak sense that there is something it feels like for the subject to experience something. In autonoetic consciousness, consciousness emerges, by definition, by retrieval of memories of personally experienced events (episodic memory). It has been shown with transcranial magnetic stimulation (TMS) that a medial paralimbic circuitry is critical for self-reference. This circuitry includes anterior cingulate/medial prefrontal and posterior cingulate/medial parietal cortices, connected directly and via thalamus. We here hypothesized that interaction in the circuitry may bind conscious experiences with widely different degrees of self-reference through synchrony of high frequency oscillations as a common neural event. This hypothesis was confirmed with magneto-encephalography (MEG). The observed coupling between the neural events in conscious experience may explain the sense of unity of consciousness and the severe symptoms associated with paralimbic dysfunction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1097-0193
pubmed:author
pubmed:copyrightInfo
(c) 2009 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-92
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Coherence in consciousness: paralimbic gamma synchrony of self-reference links conscious experiences.
pubmed:affiliation
CFIN, Aarhus University Hospital, DK-8000 Aarhus, Denmark. hl@ipm.regionh.dk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't