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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-8-4
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pubmed:abstractText |
Nausea and dysautonomic crises severely limit function and quality of life for a large number of individuals with familial dysautonomia. We treated a small cohort of 15 patients with familial dysautonomia who suffered frequent dysautonomic crises with pregabalin. Nausea and overt crises markedly decreased in 13 (87%) of these patients and the overall assessments of benefit were extremely favorable, suggesting that pregabalin may be a potentially useful therapeutic agent for this disorder.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1098-4275
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
743-6
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pubmed:meshHeading |
pubmed-meshheading:19620195-Adolescent,
pubmed-meshheading:19620195-Adult,
pubmed-meshheading:19620195-Anticonvulsants,
pubmed-meshheading:19620195-Carrier Proteins,
pubmed-meshheading:19620195-Child,
pubmed-meshheading:19620195-Dose-Response Relationship, Drug,
pubmed-meshheading:19620195-Drug Administration Schedule,
pubmed-meshheading:19620195-Drug Therapy, Combination,
pubmed-meshheading:19620195-Dysautonomia, Familial,
pubmed-meshheading:19620195-Female,
pubmed-meshheading:19620195-Humans,
pubmed-meshheading:19620195-Male,
pubmed-meshheading:19620195-Young Adult,
pubmed-meshheading:19620195-gamma-Aminobutyric Acid
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pubmed:year |
2009
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|
pubmed:articleTitle |
Pregabalin: a new approach to treatment of the dysautonomic crisis.
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pubmed:affiliation |
Department of Pediatrics, New York University School of Medicine, New York, New York 10016, USA. felicia.axelrod@nyumc.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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