Linked Life Data

19619964

Source:http://linkedlifedata.com/resource/pubmed/id/19619964

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2009-11-16
pubmed:abstractText
Streptococcus suis (S. suis) is a major swine pathogen and an emerging zoonotic agent. However, the current understanding of the S. suis pathogenesis of infection remains limited. In the present study, an IgA1 protease of S. suis was identified for the first time. The protein was recombinantly expressed in Escherichia coli, and the purified recombinant protein showed good cleaving reactivity to IgA1 and was highly immunoreactive to convalescent sera. The gene was found to exist in most pathogenic strains but scarcely in non-invasive isolates. These findings suggested that the IgA1 protease might play an important role in the pathogenesis of S. suis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1873-2542
pubmed:author
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
140
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-5
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Identification and characterization of IgA1 protease from Streptococcus suis.
pubmed:affiliation
Unit of Animal Infectious Diseases, National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, 1 Shizishan Street, Wuhan, Hubei 430070, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't