Linked Life Data

1961222

Source:http://linkedlifedata.com/resource/pubmed/id/1961222

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
26
pubmed:dateCreated
1992-1-3
pubmed:abstractText
Ataxia-telangiectasia is an autosomal recessive syndrome in which cancers develop in affected homozygotes at a rate approximately 100 times higher than in unaffected age-matched subjects. Retrospective studies have shown that persons heterozygous for the ataxia-telangiectasia gene, who make up about 1 percent of the general population, also have an excess risk of cancer, particularly breast cancer in women. Patients with ataxia-telangiectasia and cells derived from homozygotes and heterozygotes are unusually sensitive to ionizing radiation.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0028-4793
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
325
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1831-6
pubmed:dateRevised
2010-3-24
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Incidence of cancer in 161 families affected by ataxia-telangiectasia.
pubmed:affiliation
Biological Sciences Research Center, University of North Carolina, Chapel Hill 27599-7250.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.