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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2009-7-14
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pubmed:abstractText |
Gene expression can be differentially regulated by alternatively spliced transcription factors, providing a mechanism for precise control of diverse morphogenetic events. The paired-type homedomain transcription factor Prrxl1 (formerly known as Drg11) was described as a key regulator of the differentiation of the spinal cord neuronal circuit dedicated to the processing of nociceptive information. Here, we report the characterization of a Prrxl1 alternative splice variant that we termed Prrxl1-b.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1696-3547
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1089-95
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pubmed:meshHeading |
pubmed-meshheading:19598127-Alternative Splicing,
pubmed-meshheading:19598127-Amino Acid Sequence,
pubmed-meshheading:19598127-Animals,
pubmed-meshheading:19598127-Base Sequence,
pubmed-meshheading:19598127-DNA,
pubmed-meshheading:19598127-Female,
pubmed-meshheading:19598127-Gene Expression Regulation, Developmental,
pubmed-meshheading:19598127-Homeodomain Proteins,
pubmed-meshheading:19598127-In Situ Hybridization,
pubmed-meshheading:19598127-Mice,
pubmed-meshheading:19598127-Molecular Sequence Data,
pubmed-meshheading:19598127-Nerve Tissue Proteins,
pubmed-meshheading:19598127-Nervous System,
pubmed-meshheading:19598127-Nociceptors,
pubmed-meshheading:19598127-Pregnancy,
pubmed-meshheading:19598127-Protein Isoforms,
pubmed-meshheading:19598127-Protein Structure, Tertiary,
pubmed-meshheading:19598127-RNA, Messenger,
pubmed-meshheading:19598127-Sequence Homology, Amino Acid,
pubmed-meshheading:19598127-Sequence Homology, Nucleic Acid,
pubmed-meshheading:19598127-Tissue Distribution,
pubmed-meshheading:19598127-Transcription Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Expression of a Prrxl1 alternative splice variant during the development of the mouse nociceptive system.
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pubmed:affiliation |
IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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