19596916

Source:http://linkedlifedata.com/resource/pubmed/id/19596916

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007102, umls-concept:C0031715, umls-concept:C0334227, umls-concept:C0442805, umls-concept:C1411976, umls-concept:C1879547
pubmed:issue	7
pubmed:dateCreated	2009-7-14
pubmed:abstractText	Toll-like receptors (TLRs) are involved in innate immunity. Overexpression of TLRs has been implicated in various types of cancer including colorectal cancer (CRC). The phosphatidylinositol-3'-kinase (PI3K)/Akt signaling pathway is involved in CRC growth and progression. In this study, we determined whether TLR4 signaling and PI3K/Akt pathway activation occur in CRCs.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01 CA104748, http://linkedlifedata.com/resource/pubmed/grant/R01 CA104748-05, http://linkedlifedata.com/resource/pubmed/grant/R01 DK048498-14, http://linkedlifedata.com/resource/pubmed/grant/R01 DK48498
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8102988
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1791-7530
pubmed:author	pubmed-author:BowenKanika AKA, pubmed-author:DoanHung QHQ, pubmed-author:EversB MarkBM, pubmed-author:JacksonLindsey ALA
pubmed:issnType	Electronic
pubmed:volume	29
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2473-8
pubmed:dateRevised	2011-4-13
pubmed:meshHeading	pubmed-meshheading:19596916-Aged, pubmed-meshheading:19596916-Colorectal Neoplasms, pubmed-meshheading:19596916-Enzyme Activation, pubmed-meshheading:19596916-Female, pubmed-meshheading:19596916-Humans, pubmed-meshheading:19596916-Immunohistochemistry, pubmed-meshheading:19596916-Lipopolysaccharides, pubmed-meshheading:19596916-Male, pubmed-meshheading:19596916-Middle Aged, pubmed-meshheading:19596916-Phosphatidylinositol 3-Kinases, pubmed-meshheading:19596916-Phosphorylation, pubmed-meshheading:19596916-Proto-Oncogene Proteins c-akt, pubmed-meshheading:19596916-Signal Transduction, pubmed-meshheading:19596916-Toll-Like Receptor 4
pubmed:year	2009
pubmed:articleTitle	Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells.
pubmed:affiliation	Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural