19595621

Source:http://linkedlifedata.com/resource/pubmed/id/19595621

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0022742, umls-concept:C0600169, umls-concept:C1521970, umls-concept:C1533691, umls-concept:C1705241, umls-concept:C1705242
pubmed:issue	8
pubmed:dateCreated	2009-10-5
pubmed:abstractText	In vitro systems provide a powerful means to evaluate the efficacy of total knee arthroplasty (TKA) in restoring normal knee kinematics. The Oxford knee rig (OKR) and the robotic knee testing system (RKTS) represent two systems that have been extensively used to study TKA biomechanics. Nonetheless, a frequently asked question is whether in vitro simulations can capture the in vivo behavior of the knee. Here, we compared the flexion-extension kinematics of intact knees and knees after TKA tested on the OKR and RKTS, to results of representative in vivo studies. The goal was to determine if the in vitro systems could capture the key kinematic features of knees in healthy subjects and TKA patients. Results showed that the RKTS and the OKR can replicate the femoral rollback and 'screw home' tibial rotation between 0 degrees and 30 degrees flexion seen in healthy subjects, and the reduced femoral rollback and absence of 'screw home' motion in TKA patients. The RKTS also replicated the overall internally rotated position of the tibia beyond 30 degrees flexion. However, ability of the OKR to replicate the internally rotated position of the knee beyond 30 degrees flexion was inconsistent. These data could aid in validation of new in vitro systems and physiologic interpretations of in vitro results.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9422753
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1873-4030
pubmed:author	pubmed-author:HarryRubash ERE, pubmed-author:JohnsonToddT, pubmed-author:LiGuoanG, pubmed-author:VaradarajanKartik MKM
pubmed:issnType	Electronic
pubmed:volume	31
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	899-906
pubmed:meshHeading	pubmed-meshheading:19595621-Arthroplasty, Replacement, Knee, pubmed-meshheading:19595621-Biomechanics, pubmed-meshheading:19595621-Case-Control Studies, pubmed-meshheading:19595621-Humans, pubmed-meshheading:19595621-Knee
pubmed:year	2009
pubmed:articleTitle	Can in vitro systems capture the characteristic differences between the flexion-extension kinematics of the healthy and TKA knee?
pubmed:affiliation	Bioengineering Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Meta-Analysis