19594946

Source:http://linkedlifedata.com/resource/pubmed/id/19594946

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0016263, umls-concept:C0024141, umls-concept:C0030705, umls-concept:C0034809, umls-concept:C0597360, umls-concept:C0936012, umls-concept:C1167622
pubmed:issue	4
pubmed:dateCreated	2009-9-18
pubmed:databankReference	http://linkedlifedata.com/resource/pubmed/xref/ClinicalTrials.gov/NCT00600652
pubmed:abstractText	Glucocorticoid (GC) therapy is the main treatment for systemic lupus erythematosus (SLE). However, some patients are resistant to these agents. Abnormalities of glucocorticoid receptor (GR) seem to be related to steroid resistance. This study evaluated GRs in T lymphocytes and monocytes of SLE patients by flow cytometry (FCM) using a monoclonal antibody (mAb) and FITC-Dex probes.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101154438
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD14, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3, http://linkedlifedata.com/resource/pubmed/chemical/Dexamethasone, http://linkedlifedata.com/resource/pubmed/chemical/Glucocorticoids, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glucocorticoid
pubmed:status	MEDLINE
pubmed:issn	1478-6362
pubmed:author	pubmed-author:DuJuanJ, pubmed-author:FengYingluY, pubmed-author:KoçLL, pubmed-author:LingChangquanC, pubmed-author:ZEHHH, pubmed-author:ZhaiXiaofengX, pubmed-author:ZhangDenghaiD, pubmed-author:ZhangWeiweiW, pubmed-author:ZhuXiaoyanX
pubmed:issnType	Electronic
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	R108
pubmed:meshHeading	pubmed-meshheading:19594946-Adult, pubmed-meshheading:19594946-Anti-Inflammatory Agents, pubmed-meshheading:19594946-Antigens, CD14, pubmed-meshheading:19594946-Antigens, CD3, pubmed-meshheading:19594946-Blotting, Western, pubmed-meshheading:19594946-Dexamethasone, pubmed-meshheading:19594946-Drug Resistance, pubmed-meshheading:19594946-Female, pubmed-meshheading:19594946-Flow Cytometry, pubmed-meshheading:19594946-Glucocorticoids, pubmed-meshheading:19594946-Humans, pubmed-meshheading:19594946-Lupus Erythematosus, Systemic, pubmed-meshheading:19594946-Male, pubmed-meshheading:19594946-Middle Aged, pubmed-meshheading:19594946-Monocytes, pubmed-meshheading:19594946-Receptors, Glucocorticoid, pubmed-meshheading:19594946-T-Lymphocytes
pubmed:year	2009
pubmed:articleTitle	Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus.
pubmed:affiliation	Department of Integrative Medicine, Changhai Hospital, The Second Military Medicine University, No. 168 Changhai Road, Shanghai, PR China. dujuan714@163.com
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't