Linked Life Data

19593586

Source:http://linkedlifedata.com/resource/pubmed/id/19593586

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-7-24
pubmed:abstractText
The four different forms of human malaria have threatened humanity since time immemorial and to this day, they exact a death toll of one to three million people annually. Synthetic anti-malarial agents have been in development since early 1900. Perhaps the most successful and widely used drug, Resochin (chloroquine), was discovered 75 years ago; for a long time, it was the drug of choice and to this day, it is still used in many regions of the world as a reliable treatment against simpler forms of malaria. In regions where it has not been in use against malaria tropica for quite some time due to the development of resistances, it has regained some of its efficacy. This review traces the discovery and the mechanism of action of this substance, illustrates the significance of malaria today, and underlines the need for controlled and reliable therapeutic measures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1432-1955
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
609-27
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Seventy-five years of Resochin in the fight against malaria.
pubmed:affiliation
Bayer Vital GmbH, Kaiser Wilhelm Allee, 51368, Leverkusen, Germany. Markus.Jensen@bayerhealthcare.com
pubmed:publicationType
Journal Article, Review, Historical Article