19592568

Source:http://linkedlifedata.com/resource/pubmed/id/19592568

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003209, umls-concept:C0026809, umls-concept:C0034693, umls-concept:C0212997, umls-concept:C2936381
pubmed:issue	3
pubmed:dateCreated	2009-11-17
pubmed:abstractText	Bindarit is an original compound with peculiar anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines, including the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8. In this study, we investigated the effect of bindarit on neointima formation using two animal models of arterial injury: rat carotid artery balloon angioplasty and wire-induced carotid injury in apolipoprotein E-deficient (apoE(-/-)) mice.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0077427
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E, http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2, http://linkedlifedata.com/resource/pubmed/chemical/Indazoles, http://linkedlifedata.com/resource/pubmed/chemical/Propionic Acids, http://linkedlifedata.com/resource/pubmed/chemical/bindarit
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1755-3245
pubmed:author	pubmed-author:BiondiGiuseppeG, pubmed-author:GrassiaGianlucaG, pubmed-author:GuglielmottiAngeloA, pubmed-author:IalentiArmandoA, pubmed-author:MaddalunoMarcellaM, pubmed-author:MaffiaPasqualeP, pubmed-author:ManganoGiorginaG
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	84
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	485-93
pubmed:dateRevised	2010-9-27
pubmed:meshHeading	pubmed-meshheading:19592568-Animals, pubmed-meshheading:19592568-Anti-Inflammatory Agents, pubmed-meshheading:19592568-Apolipoproteins E, pubmed-meshheading:19592568-Carotid Arteries, pubmed-meshheading:19592568-Carotid Artery Injuries, pubmed-meshheading:19592568-Cell Movement, pubmed-meshheading:19592568-Cell Proliferation, pubmed-meshheading:19592568-Cells, Cultured, pubmed-meshheading:19592568-Chemokine CCL2, pubmed-meshheading:19592568-Disease Models, Animal, pubmed-meshheading:19592568-Female, pubmed-meshheading:19592568-Hyperlipidemias, pubmed-meshheading:19592568-Indazoles, pubmed-meshheading:19592568-Male, pubmed-meshheading:19592568-Mice, pubmed-meshheading:19592568-Mice, Knockout, pubmed-meshheading:19592568-Muscle, Smooth, Vascular, pubmed-meshheading:19592568-Propionic Acids, pubmed-meshheading:19592568-Rats, pubmed-meshheading:19592568-Rats, Wistar
pubmed:year	2009
pubmed:articleTitle	The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice.
pubmed:affiliation	Department of Experimental Pharmacology, University of Naples Federico II, Via Domenico Montesano, 49, 80131 Naples, Italy.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't