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pubmed-article:19592464pubmed:abstractTextArterial injury induces smooth muscle cell (SMC) proliferation, migration, and intimal accumulation of cells and extracellular matrix. These processes are regulated by the administration of the glycosaminoglycans heparin and heparan sulfate, but little is known about the role of endogenous heparan sulfate proteoglycans in the vessel wall. We investigated the response to carotid injury of syndecan-1-null mice to assess the function of one of a conserved family of transmembrane heparan and chondroitin sulfate proteoglycans.lld:pubmed
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pubmed-article:19592464pubmed:articleTitleSyndecan-1: an inhibitor of arterial smooth muscle cell growth and intimal hyperplasia.lld:pubmed
pubmed-article:19592464pubmed:affiliationDepartment of Surgery and Center for Cardiovascular Biology, University of Washington, Seattle, WA 98195-6410, USA.lld:pubmed
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