Linked Life Data

19589911

Source:http://linkedlifedata.com/resource/pubmed/id/19589911

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-9-21
pubmed:abstractText
Crooke's cell adenoma (CCA), characterized by massive Crooke's hyaline change in corticotroph adenoma, causes a rare subtype of Cushing's disease. In contrast to ordinary corticotroph adenomas, CCAs are generally aggressive and present as invasive macroadenomas, which are refractory to both surgery and radiotherapy and have a high-recurrence rate. Moreover, some patients with CCA present with distant or craniospinal metastases. Currently, there are no effective standard therapies for CCA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1479-683X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
161
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
553-9
pubmed:meshHeading
pubmed-meshheading:19589911-Adolescent, pubmed-meshheading:19589911-Adrenocorticotropic Hormone, pubmed-meshheading:19589911-Adult, pubmed-meshheading:19589911-Aged, pubmed-meshheading:19589911-Antineoplastic Agents, Alkylating, pubmed-meshheading:19589911-Dacarbazine, pubmed-meshheading:19589911-Female, pubmed-meshheading:19589911-Humans, pubmed-meshheading:19589911-Hydrocortisone, pubmed-meshheading:19589911-Immunohistochemistry, pubmed-meshheading:19589911-Liver Neoplasms, pubmed-meshheading:19589911-Male, pubmed-meshheading:19589911-Middle Aged, pubmed-meshheading:19589911-O(6)-Methylguanine-DNA Methyltransferase, pubmed-meshheading:19589911-Pituitary ACTH Hypersecretion, pubmed-meshheading:19589911-Pituitary Neoplasms, pubmed-meshheading:19589911-Tomography, X-Ray Computed, pubmed-meshheading:19589911-Young Adult
pubmed:year
2009
pubmed:articleTitle
High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing's disease.
pubmed:affiliation
Department of Endocrinology and Metabolism, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, Japan. coactivator@mac.com
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't