Linked Life Data

19588955

Source:http://linkedlifedata.com/resource/pubmed/id/19588955

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
2009-9-8
pubmed:abstractText
The colloidal stability of gold nanoparticles (AuNPs) cap-exchanged with either monothiol- or dithiolane-terminated PEG-OCH(3) ligands was investigated. Three distinct aspects were explored: (1) effects of excess salt concentration; (2) ligation competition by dithiothreitol (DTT); and (3) resistance to sodium cyanide digestion. We found that overall ligands presenting higher coordination numbers (dithiolane) exhibit much better stability to excess added salt and against competition from DTT compared to their monodentate counterparts. Resistance to NaCN digestion indicated that there is a balance between coordination number and density of ligand packing on the NP surface. For smaller NPs, where a larger surface curvature reduces the ligand packing density, a higher coordination number is clearly beneficial. In comparison, a higher ligand density allowed by the smaller curvature for larger nanocrystals makes monothiol-PEG-capped NPs more resistant to cyanide digestion. The present study indicates that balance between the coordination number and surface packing density is crucial to enhancing the colloidal stability of AuNPs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0743-7463
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10604-11
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Effects of ligand coordination number and surface curvature on the stability of gold nanoparticles in aqueous solutions.
pubmed:affiliation
Division of Optical Sciences, Naval Research Laboratory, Washington, DC 20375, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't