Linked Life Data

19588101

Source:http://linkedlifedata.com/resource/pubmed/id/19588101

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-7-9
pubmed:abstractText
A series of large-scale Arabidopsis thaliana microarray expression experiments profiling genome-wide expression across different developmental stages, cell types, and environmental conditions have resulted in tremendous amounts of gene expression data. This gene expression is the output of complex transcriptional regulatory networks and provides a starting point for identifying the dominant transcriptional regulatory modules acting within the plant. Highly co-expressed groups of genes are likely to be regulated by similar transcription factors. Therefore, finding these co-expressed groups can reduce the dimensionality of complex expression data into a set of dominant transcriptional regulatory modules. Determining the biological significance of these patterns is an informatics challenge and has required the development of new methods. Using these new methods we can begin to understand the biological information contained within large-scale expression data sets.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1940-6029
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
553
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-77
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Manipulating large-scale Arabidopsis microarray expression data: identifying dominant expression patterns and biological process enrichment.
pubmed:affiliation
Department of Biology, Duke University, Durham, NC, USA.
pubmed:publicationType
Journal Article, Review