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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-7-9
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pubmed:abstractText |
The glycosphingolipid beta-galactosylceramide-3-O-sulfate (sulfatide) is present in the secretory granules of the insulin producing beta-cells and may act as a molecular chaperone of insulin. The final step in sulfatide synthesis is performed by cerebroside sulfotransferase (CST) (EC 2.8.2.11). The aim of this study was to investigate whether two single nucleotide polymorphisms (SNP), rs2267161 located in an exon or rs42929 located in an intron, in the gene encoding CST are linked to type 2 diabetes (T2D).
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-10437800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-10480608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-10570222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-10973253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-11017071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-11445552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-12829657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-14673476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-14749263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-14988270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-15019291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-15855351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-15892652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-16108848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-16123500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-16143863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-16415884,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-16622298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-3899825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-8117740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-9048875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-9541507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19587831-9929969
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1687-5303
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2009
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429593
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19587831-Adult,
pubmed-meshheading:19587831-Aged,
pubmed-meshheading:19587831-Blood Glucose,
pubmed-meshheading:19587831-Body Mass Index,
pubmed-meshheading:19587831-Diabetes Mellitus, Type 2,
pubmed-meshheading:19587831-Exercise,
pubmed-meshheading:19587831-Female,
pubmed-meshheading:19587831-Gene Frequency,
pubmed-meshheading:19587831-Genetic Predisposition to Disease,
pubmed-meshheading:19587831-Glucose Tolerance Test,
pubmed-meshheading:19587831-Homeostasis,
pubmed-meshheading:19587831-Humans,
pubmed-meshheading:19587831-Insulin,
pubmed-meshheading:19587831-Insulin Resistance,
pubmed-meshheading:19587831-Male,
pubmed-meshheading:19587831-Middle Aged,
pubmed-meshheading:19587831-Polymorphism, Single Nucleotide,
pubmed-meshheading:19587831-Questionnaires,
pubmed-meshheading:19587831-Sulfoglycosphingolipids,
pubmed-meshheading:19587831-Sulfotransferases,
pubmed-meshheading:19587831-Sweden
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pubmed:year |
2009
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pubmed:articleTitle |
A variation in the cerebroside sulfotransferase gene is linked to exercise-modified insulin resistance and to type 2 diabetes.
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pubmed:affiliation |
Bartholin Institute, Rigshospitalet, Ole Maaløvsvej 5, 2200 Copenhagen, Denmark. allan@roeske.dk
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pubmed:publicationType |
Journal Article
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