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pubmed-article:19581416 | lifeskim:mentions | umls-concept:C2697811 | lld:lifeskim |
pubmed-article:19581416 | lifeskim:mentions | umls-concept:C2936350 | lld:lifeskim |
pubmed-article:19581416 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
pubmed-article:19581416 | lifeskim:mentions | umls-concept:C1423062 | lld:lifeskim |
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pubmed-article:19581416 | lifeskim:mentions | umls-concept:C1550501 | lld:lifeskim |
pubmed-article:19581416 | pubmed:issue | 10 | lld:pubmed |
pubmed-article:19581416 | pubmed:dateCreated | 2009-10-1 | lld:pubmed |
pubmed-article:19581416 | pubmed:abstractText | Atherosclerosis is accelerated in subjects with type 2 diabetes by unknown mechanisms. We identified tissue inhibitor of metalloproteinase 3 (TIMP3), the endogenous inhibitor of A disintegrin and metalloprotease domain 17 (ADAM17) and other matrix metalloproteinases (MMPs), as a gene modifier for insulin resistance and vascular inflammation in mice. We tested its association with atherosclerosis in subjects with type 2 diabetes and identified Sirtuin 1 (SirT1) as a major regulator of TIMP3 expression. | lld:pubmed |
pubmed-article:19581416 | pubmed:language | eng | lld:pubmed |
pubmed-article:19581416 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19581416 | pubmed:citationSubset | AIM | lld:pubmed |
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pubmed-article:19581416 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19581416 | pubmed:month | Oct | lld:pubmed |
pubmed-article:19581416 | pubmed:issn | 1939-327X | lld:pubmed |
pubmed-article:19581416 | pubmed:author | pubmed-author:SoliniAnnaA | lld:pubmed |
pubmed-article:19581416 | pubmed:author | pubmed-author:FolliFrancoF | lld:pubmed |
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pubmed-article:19581416 | pubmed:author | pubmed-author:LauroRenatoR | lld:pubmed |
pubmed-article:19581416 | pubmed:author | pubmed-author:MenghiniRosse... | lld:pubmed |
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pubmed-article:19581416 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:19581416 | pubmed:volume | 58 | lld:pubmed |
pubmed-article:19581416 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19581416 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19581416 | pubmed:pagination | 2396-401 | lld:pubmed |
pubmed-article:19581416 | pubmed:dateRevised | 2010-10-4 | lld:pubmed |
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pubmed-article:19581416 | pubmed:year | 2009 | lld:pubmed |
pubmed-article:19581416 | pubmed:articleTitle | TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. | lld:pubmed |
pubmed-article:19581416 | pubmed:affiliation | Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy. | lld:pubmed |
pubmed-article:19581416 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19581416 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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